Conclusions

Primary mesenteric NET is an exceptionally rare entity that poses significant diagnostic and therapeutic challenges. Accurate diagnosis requires a combination of cross-sectional imaging, thorough intraoperative exploration, histopathological evaluation, and immunohistochemical profiling. Complete surgical excision remains the treatment of choice, and postoperative surveillance with functional imaging is imperative to guide further management. Reporting of such rare cases contributes to the growing body of literature that may inform future diagnostic and management guidelines.