Work overview

Section 04 of 11

Treatment

Septic Pylephlebitis and Cavernous Transformation Presenting as Pyrexia of Unknown Origin: A Diagnostic Challenge

Aditi Sarker, Prodipta Chowdhury, and Md. Razibul Alam · 2026

Contents

Section 04 of 11

  1. 01Introduction
  2. 02Case Presentation and Clinical Examination
  3. 03Differential Diagnosis, Investigations and Diagnosis
  4. 04Treatment
  5. 05Outcome and Follow‐Up
  6. 06Discussion
  7. 07Author Contributions
  8. 08Funding
  9. 09Ethics Statement
  10. 10Consent
  11. 11Conflicts of Interest
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Work overview

Section 4 of 11

Treatment

Aditi Sarker, Prodipta Chowdhury, and Md. Razibul Alam · about 1 minutes

Original source ↗

The patient received intravenous broad‐spectrum antibiotics (Ceftriaxone 2 g twice daily for 02 weeks) and supportive care, with defervescence and improvement in inflammatory markers. Therapeutic anticoagulation (rivaroxaban 10 mg once daily for 03 months) was initiated after endoscopic documentation of Grade II‐III esophageal varices and individual bleeding‐risk assessment. Because cavernous transformation coexisted with biliary dilatation and portal hypertensive changes, portal cavernoma cholangiopathy (portal biliopathy) was considered, and the patient was managed conservatively with portal hypertension prophylaxis and multidisciplinary follow‐up.