Work overview

Section 02 of 11

Case Presentation and Clinical Examination

Septic Pylephlebitis and Cavernous Transformation Presenting as Pyrexia of Unknown Origin: A Diagnostic Challenge

Aditi Sarker, Prodipta Chowdhury, and Md. Razibul Alam · 2026

Contents

Section 02 of 11

  1. 01Introduction
  2. 02Case Presentation and Clinical Examination
  3. 03Differential Diagnosis, Investigations and Diagnosis
  4. 04Treatment
  5. 05Outcome and Follow‐Up
  6. 06Discussion
  7. 07Author Contributions
  8. 08Funding
  9. 09Ethics Statement
  10. 10Consent
  11. 11Conflicts of Interest
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Work overview

Section 2 of 11

Case Presentation and Clinical Examination

Aditi Sarker, Prodipta Chowdhury, and Md. Razibul Alam · about 1 minutes

A 45‐year‐old male farmer, non‐diabetic and non‐smoker, was referred with unintentional weight loss and malaise. On initial query, he did not volunteer focal biliary symptoms, but he reported a history of irregular fever over the preceding two months. On admission, he was febrile at 37.8°C (100°F), while the remaining vital signs were stable. The patient was not icteric, had no organomegaly, and had no lymphadenopathy.

Before referral, he had been treated empirically for presumed enteric fever and later put on prednisolone 1 mg/kg/day without a steroid‐sparing agent for suspected adult‐onset Still's disease. The fever transiently subsided, but he again became febrile within 02 weeks, so prednisolone was discontinued. His overall condition and weight loss did not improve.