Work overview

Section 01 of 06

Key Points

Comparative effectiveness of high-dose versus standard-dose influenza vaccines in nursing home residents aged 65 and older in France: a nationwide cohort study on the French health data system from the 2022–2023 season

Helene Bricout, Marie-Cecile Levant, Pascal Crépey, Gaëtan Gavazzi, Jacques Gaillat, Marine Dufournet, Nada Assi, Benjamin Grenier, Fanny Raguideau, Camille Salamand, Anne Mosnier, Laurence Watier, Odile Launay, and Matthew Loiacono · 2026

Contents

Section 01 of 06

  1. 01Key Points
  2. 02Introduction
  3. 03Methods
  4. 04Results
  5. 05Discussion
  6. 06Conclusion
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Work overview

Section 1 of 6

Key Points

Helene Bricout, Marie-Cecile Levant, Pascal Crépey, Gaëtan Gavazzi, Jacques Gaillat, Marine Dufournet, Nada Assi, Benjamin Grenier, Fanny Raguideau, Camille Salamand, Anne Mosnier, Laurence Watier, Odile Launay, and Matthew Loiacono · about 1 minutes

  • Nationwide cohort study using SNDS compared high-dose (HD) versus standard-dose (SD) influenza vaccine effectiveness.
  • HD influenza vaccine was associated with a significant reduction in influenza-related hospitalisations in French nursing homes.
  • Relative vaccine effectiveness for influenza hospitalisations was 30.8% (95% CI: 11.8–45.7; P = .0029).
  • Findings support preferential use of high-dose influenza vaccines in institutionalised older populations.