Work overview

Section 09 of 09

Supporting information

Irritable Bowel Disease: Think Malonic and Methylmalonic Aciduria (CMAMMA)!

Khaled Alatibi, Martin J. Hug, and Sara Tucci · 2026

Contents

Section 09 of 09

  1. 01Introduction
  2. 02Results
  3. 03Results
  4. 04Discussion
  5. 05Conclusions
  6. 06Author Contributions
  7. 07Funding
  8. 08Conflicts of Interest
  9. 09Supporting information
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Work overview

Section 9 of 9

Supporting information

Khaled Alatibi, Martin J. Hug, and Sara Tucci · about 1 minutes

Original source ↗

Figure S1: (A) Simplified schematic representation and working hypothesis of amino acid metabolism in CMAMMA. Cellular localization of the metabolic pathways and involvement of all additional pathways are not presented. The schematic representation was made using Biorender (https://www.biorender.com/). (B) Timeline with relevant information for the diagnosis of the patient. The schematic representation was made using Biorender (https://www.biorender.com/). (C) Global malonylation degree of cellular proteins detected with the anti‐malonylated lysine antibody. The arrows indicate protein bands that show a visibly stronger malonylation signal in patient‐derived fibroblasts compared to controls.