Section 5 of 6
Conclusion
Roza C. M. Opperman, Sofie Bosch, Eduard A. Struys, Awa Hassan, Faridi S. Jamaludin, Tim G. J. de Meij, Evelien Dekker, and Nanne K. H. de Boer · about 1 minutes
In conclusion, individual amino acids do not appear to have sufficient diagnostic accuracy to serve as standalone biomarkers for CRC. Instead, amino acids profiling may be more informative when incorporated in multivariate panels that include other metabolite classes as well. Although tissue-based studies show the most consistent amino acid alterations, their limited suitability for non-invasive screening highlights the importance of translating these metabolic insights into clinically applicable biomarker panels.