AUTHORS’ CONTRIBUTIONS

SRA: Conceptualized the study, conducted the experiment, performed molecular and laboratory analyses, analyzed the data, interpreted the results, and drafted the manuscript. ML: Conceived and supervised the study, interpreted the findings, and critically revised the manuscript. SHW and MAAA: Designed the experimental methodology, analyzed and interpreted the data, and critically edited the manuscript. EJK and SS: Contributed to data interpretation, critically reviewed the scientific content, and revised the manuscript. LL: Assisted with molecular data interpretation, reviewed the manuscript, and edited the references. ARK: Assisted with literature review, reference management, and manuscript editing. All authors have read and approved the final manuscript.