Work overview

Section 02 of 08

Case History/Examination

Aceruloplasminemia Presenting With Prominent Psychiatric Symptoms and Neurodegeneration: A Case Report

Ali Almarzooqi, Abdulrahman Almarzooqi, Khalifa Juma, and Hamda Kamalboor · 2026

Contents

Section 02 of 08

  1. 01Introduction
  2. 02Case History/Examination
  3. 03Methods
  4. 04Conclusion and Results (Outcome and Follow‐Up)
  5. 05Discussion
  6. 06Author Contributions
  7. 07Funding
  8. 08Consent
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Work overview

Section 2 of 8

Case History/Examination

Ali Almarzooqi, Abdulrahman Almarzooqi, Khalifa Juma, and Hamda Kamalboor · about 1 minutes

Original source ↗

The patient was a 50‐year‐old Emirati male born to consanguineous parents (first‐degree cousins). There was no family history of similar neurological or psychiatric disorders. He had been diagnosed with type 2 diabetes mellitus 10 years earlier, likely related to pancreatic iron overload, and was treated with sitagliptin and metformin. Glycemic control was poor due to inconsistent adherence.

Psychiatric and Neurological Course (TIMELINE)

2013: Diabetes mellitus diagnosed, consistent with an early systemic feature of ACP.2020–2021: He developed psychiatric symptoms including paranoia, persecutory delusions, irritability, crying spells, and simple visual and auditory hallucinations. He was hospitalized for 1 month and discharged on escitalopram, haloperidol, and procyclidine.2021–2022: He developed neurological decline with rigidity, tremors, gait impairment, dysphagia, incontinence, and worsening memory. The Montreal Cognitive Assessment (MoCA) score was 11/30 at first follow‐up.